These options enable a top-loading sterilizer to be tailored to the needs of the customer by speeding up cooling, dealing with liquids, and porous-type loads and allowing a wider range of items to be efficiently processed
The use of UV transilluminators for the detection of DNA or RNA in agarose gels, is still very common, although we know quite well that the shorter the wavelength is, the more the DNA will be damaged quickly, which is dangerous especially if the separated DNA should be used in downstream experiments like cloning or sequencing. Just seconds of UV light is enough to reduce the cloning efficiency significantly.
In contrast to UV instruments, the new innovative LED technology uses a much higher wavelength, which means energy-less light. This will lead to the fact that the nucleic acids are not damaged but sometimes sensitivity is lower as compared to UV light. Furthermore, regular BLUE LED technology is working well with green dyes but couldn’t be recommended with red dyes like Ethidium Bromide, because the longer wavelength is favourable for green dyes but not for red components.
The VARIANTnbs is the established worldwide standard in automated newborn screening for sickle cell disease and other haemoglobin disorders. It features fully automated analysis and advanced result reporting for maximum efficiency. Using dried blood spot specimens, the VARIANTnbs identifies the most clinically significant haemoglobin variants, including haemoglobins F, S, A, C, D and E, as well as the carrier status for abnormal haemoglobin variants and many double-heterozygote conditions. The VARIANTnbs provide the total haemoglobin picture.
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